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et’s disease in a Chinese population

Shengping Hou, Aize Kijlstra, Peizeng Yang

Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 354-359 doi: 10.1007/s11684-012-0234-2

Abstract: et’s disease is defined as a multisystemic inflammatory disease.Although the precise pathogenesis and etiology is still a mystery, accumulating evidence shows that geneticet’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?These genetic predisposition studies support an important role for both lymphocyte differentiation as

Keywords： et’s disease SNPs immune gene genetic study

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Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases

Xia Jiahui

Strategic Study of CAE 2000, Volume 2, Issue 11, Pages 1-11

Abstract: paper, the study on family collection, gene mapping, gene identification and gene function of human geneticSince 1991, 590 families with 345 kind of genetic diseases were collected.In 1998, GJB3, a human genetic neurological deafness gene, was identified using a novel strategy of “Gene Family-Candidate Disease Gene Cloning”，and the paper was published in Nature Genetics

Keywords： genetic disease gene mapping and cloning gene familiy-candidate disease gene cloning genome wide scan

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Machine learning modeling identifies hypertrophic cardiomyopathy subtypes with genetic signature

Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 768-780 doi: 10.1007/s11684-023-0982-1

Abstract: By employing echocardiography and genetic screening for the 46 genes, HCM can be classified into two

Keywords： machine learning methods hypertrophic cardiomyopathy genetic risk

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Interplay between diet and genetic susceptibility in obesity and related traits

Tiange Wang, Min Xu, Yufang Bi, Guang Ning

Frontiers of Medicine 2018, Volume 12, Issue 6, Pages 601-607 doi: 10.1007/s11684-018-0648-6

Abstract: Longitudinal studies and randomized intervention trials have shown that genetic susceptibility to obesity

Keywords： diet genetic susceptibility obesity interaction

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Optimal design of steel skeletal structures using the enhanced genetic algorithm methodology

Tugrul TALASLIOGLU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 4, Pages 863-889 doi: 10.1007/s11709-019-0523-9

Abstract: For this purpose, the enhanced genetic algorithm methodology named EGAwMP is utilized as an optimizationThe evolutionary search mechanism of EGAwMP is constituted on the basis of generational genetic algorithminto sub-populations and using of a radial basis neural network for dynamically adjustment of EGAwMP’s genetic

Keywords： design optimization genetic algorithm multiple populations neural network

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Research progress on genetic improvement of

Chuanping YANG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4, Pages 391-401 doi: 10.15302/J-FASE-2017183

Abstract: Over the past 30 years, effective progress has been made in genetic improvement and molecular breedingmolecular markers were developed and the high density genetic map constructed.All this research has provided a model and data for the foundation of forest genetic improvement and

Keywords： Betula platyphylla genetic improvement molecular breeding seed orchard

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Genomics and genetic breeding in aquatic animals: progress and prospects

Wenteng XU, Songlin CHEN

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3, Pages 305-318 doi: 10.15302/J-FASE-2017154

Abstract: focuses on dissection of genome structure and function to provide a molecular basis for understanding the geneticprogress of aquatic animals in nine aspects, including WGS and fine mapping, construction of high density genetic

Keywords： aquaculture genomics genetic breeding progress

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Search-and-replace editing of genetic information

Yao LIU, Xingxu HUANG, Xiaolong WANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 231-232 doi: 10.15302/J-FASE-2020322

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Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Frontiers of Medicine 2013, Volume 7, Issue 4, Pages 425-432 doi: 10.1007/s11684-013-0295-x

Abstract:

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality

Keywords： chronic obstructive pulmonary disease heterogeneity phenotype genotype prediction

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Chao SUN, Meng LAI, Shougong ZHANG, Xiaomei SUN

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4, Pages 482-492 doi: 10.15302/J-FASE-2017184

Abstract: With the aim of performing efficient early selection for wood properties, we investigated genetic variationAfter the age of 6, genetic correlations were generally higher than phenotypic correlations.

Keywords： early selection genetic variation wood properties SilviScan Larix kaempferi

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Optimal design of steel portal frames based on genetic algorithms

CHEN Yue, HU Kai

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 4, Pages 318-322 doi: 10.1007/s11709-008-0055-1

Abstract: set of constraints of the Technical Specification for Light-weighted Steel Portal Frames of China, a geneticFinally, some examples illustrate the effectiveness and efficiency of the genetic-algorithm-based optimal

Keywords： satisfactory genetic-algorithm-based Technical Specification algorithm efficiency

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Acupuncture for the management of dry eye disease

Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 975-983 doi: 10.1007/s11684-022-0923-4

Abstract: The effectiveness of using acupuncture for dry eye disease (DED) is controversial.outcomes of interests were (1) to evaluate the efficacy of acupuncture in improving the ocular surface disease

Keywords： dry eye disease xerophthalmus acupuncture

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Optimal design of double-layer barrel vaults using genetic and pattern search algorithms and optimized

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 3, Pages 378-395 doi: 10.1007/s11709-022-0899-9

Abstract: The algorithms considered in this step are the arithmetic optimization algorithm (AOA) and genetic algorithm

Keywords： optimization surrogate models artificial neural network SAP2000 genetic algorithm

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Advances in genetic engineering of domestic animals

Shaohua WANG,Kun ZHANG,Yunping DAI

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1, Pages 1-10 doi: 10.15302/J-FASE-2016085

Abstract: Thus, genetic engineering of domestic animals presents a critical and valuable tool to address theseOverall, genetic engineering has evolved through three stages in history: transgenesis, gene targetingSince the birth of the first transgenic pig, genetic engineering in livestock has been advancing slowlyRecently, rapid progress in tools and methods of genome engineering has been made, allowing genetic editingHere, we review the major advances of genetic engineering in domestic animals with emphasis placed on

Keywords： CRISPR TALEN ZFN gene editing livestock pig cattle

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Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 1, Pages 2-12 doi: 10.15302/J-FEM-2015002

Abstract: the status of major chronic diseases in China, analyzing the key issues and key factors in chronic diseasethe previous projects, this paper proposes the following recommendations as strategies for chronic diseaseWork norms and requirements will then improve the performance and efficiency in chronic disease prevention

Keywords： chronic disease prevention and control strategy and system construction